- Scentiv Llc/ Aura Candle Bar
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- Secrets
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- Security Shop INC
- See It All Sightseeing , LLC
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- Select Cut Steakhouse, INC.
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- Send Them Chicago
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- Skylar M. Sprague
- Slamdunk Food Mart, INC.
- Sliced Chi, LLC
- Sluggers
- Sluggers Grill
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- Smart Association Management LLC
- Smart Paws Chicago
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- Smiling Bright
- Smog
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- Smoke Daddy Wrigleyville
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- Smoke Shop Novelties And Stuff
- Smoke Studio
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- Smokepost
- Smoker's Zone
- Smokers Zone
- Smokers Zone
- Smoking Amsterdam
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- Smooth Electrolysis LLC
- Smoothie Joint
- Smoothie King
- Smushface Goods
- Smylie Brothers Brewing Company
- Snow And Graham LLC
- Snuggles Cleaners
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- Soli Grill
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- Sound Life LLC
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- Southern France Patisserie
- Southport Beer Wine & Spirits
- Southport Betty's
- Southport Fitness
- Southport Fundamentals
- Southport Grocery & Cafe
- Southport Grocery And Cafe, INC.
- Southport Lanes INC
- Southport Smoke & Novelties
- Spa Ave
- Spa Avenue
- Spa Spot
- Spaderma
- Sparrow Sound Design
- Spirit Halloween Superstores, LLC
- Splash Chicago
- Splendid Lemonade
- Sportclips Clybourn
- Sports Corner
- Sports Performance Innovation LLC
- Sports World
- Sportsclips Haircuts
- Ssdeals, INC.
- Sss Auto, INC.
- Stage 773
- Staircase LLC
- Stan Chan Consulting
- Stan's Donuts - Clark St.
- Stan's Donuts & Coffee
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- Stanley Williams
- Starbucks Coffee
- Starbucks Coffee #48615
- Starevents, INC.
- Stark Scott Studio LLC
- Stars & Garters
- Stars And Garters
- Starz Puzzles, LLC
- State Street Barbers
- Status Signature Salon
- Steingold's Bagels & Nosh
- Steingold's Of Chicago
- Stella Blue Design
- Stella's Diner
- Stella's Diner
- Stellar Granola
- Stephanie Fradin
- Stephen Kuhn
- Stephen Zachary Sorrow
- Steven Edward Paulus
- Steven Mcdonald
- Stitch | Stitch Monograms
- Stix Pretzels
- Stolen Saddle
- Storage One Incorporated
- Storystudio Chicago
- Strategic Philanthropy, LTD
- Street Performer
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- Stringfellow Interiors
- Strings Ramen
- Strong Hands Gym
- Strong Hands Gym, LTD.
- Strong Pilates
- Studio 32, Inc..
- Studio Abscura LLC
- Studio Cma
- Studio Forma
- Studio Gioia
- Studio Within
- Studio Workshop Collective LLC
- Stylez_by_steph
- Stylish Kitchen & Bath Cabinets
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- Subway
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- Subway
- Subway
- Subway
- Subway
- Subway
- Subway Sandwich Shop
- Subway Sandwiches #22222
- Sugar Blow, LLC
- Sugarwax LLC
- Suguni Sushi
- Sumac INC.
- Sumo Sushi And Hibachi
- Sumo Sushi Hibachi
- Sunny G Stitches