- Rt Specialty
- Ruby Gilmore
- Ruido Company, LLC
- Runner Collective LLC
- Rush Physical Therapy
- Rush Specialty Hospital
- Rush University Medical Center Bookstore
- Ruth Brown Collection, INC.
- Rwe Us Holdings, LLC
- Ryan Companies Us, INC.
- Ryan Courtwright
- Ryota
- S-valet Parking
- S.c. Johnson & Son, INC.
- S.n. Peck Builder, INC.
- Saalar On Taylor
- Sabal Capital Partners, LLC
- Sac Wireless, LLC
- Sacred Heart Phlebotomy
- Safari Cup Coffee, INC.
- Safer Foundation
- Sage Greenlife
- Saigon Sisters
- Saint Lou's Assembly & Moneygun
- Saint Patrick's Fundraiser
- Salon 939
- Salon Dj
- Salon Lofts
- Saltmara West Loop
- Sam's Quick Stop Food
- Sampco
- San Spa
- Sanderson & Associates
- Sandra Jackson
- Sandwichqueen Express
- Sandy's Pet Spa
- Sang's Kitchen
- Sangamonroe LLC
- Santorini
- Sapita Music, LLC
- Sara Young Wang LLC
- Sarah Eileen Coughlin
- Sarofsky
- Sarpinos Loop
- Sassafras Enterprises
- Sat Nam Yoga Chicago
- Sauced
- Sbarro
- Sbarro
- Scafuri Bakery
- Scale Model Studios INC. (17, 000 Sq. Ft.)
- Schatz Services, LLC
- Schavaki M Wallace
- Scheck & Siress Prosthetics, INC.
- Scherer Leadership Consulting LLC
- Schlotzskys
- School Of Hope Foundation
- Schoolrise LLC
- Scio At The Medical District
- Scoopera
- Scout Veterinary Urgent Care
- Scoutware, LLC
- Scrappychicagollc
- Scrub Depot Chicago
- Sdg Dubu So Gong Dong Tofu & Bbq
- Seafood Junction
- Sean Mclaughlin
- Sean T. Engelbreit
- Seasons Sparkling
- Second City Flooring LLC
- Second To None Tattoo Chicago
- Securit-e Intel INC.
- See Chicago Dance
- Selbert Perkins Design, INC.
- Select Development INC.
- Sepia
- Serenade Strings
- Serve Operating Co.
- Server Farm Realty
- Sg Facial Plastic Surgery
- Shades By Shosh
- Shake Shack
- Shake Shack
- Shareasale.com, INC.
- Sharelink, INC.
- Shayda Shams
- Shebuild Solutions
- Shell
- Shell
- Shell
- Shen Milsom & Wilke
- Sheri Cox Mua
- Shiny Cleaners
- Shipbob
- Shipping And Beyond
- Shoe Doctor Chicago
- Shoppertrak Rct Corporation
- Shout Outdoor Illinois, LLC
- Showingtime.com, INC.
- Siam Meats, INC.
- Sid's Clothing And Hat Store INC.
- Sie Staffing Co.
- Siebel Institute Of Technology
- Siebel Institute Of Technology
- Sight And Sound
- Silver Crown LLC
- Silver Square Consulting
- Simflex Services
- Simmerdown
- Sims Metal Management
- Sinai Community Institute
- Sinha, LTD
- Sinta
- Sips
- Siri Indian Restaurant
- Sisram Wellness Center
- Sit Stay Wash
- Sizzling Pot King
- Sj Starzz/x'pectationz LLC
- Skin By Zana, INC.
- Skin Devotion's By Dana Marie
- Skin Therapy
- Skip's Enterprise Services LLC
- Skytech Security Services
- Slg Innovation, INC.
- Slightly Toasted
- Slowear
- Sm Service Group INC DBA Nonstop Locksmith
- Smade, INC.
- Small Cheval
- Small Cheval
- Smaller Things
- Smart Technology Services, Incorporated
- Smiling Sole
- Smiling Sole, INC.
- Smith Maintenance Company
- Smitten Boutique
- Smoke Shop Pipes & Stuff
- Smokepost
- Smooth And Social
- Smoothie King
- Smx Cargo, LLC
- Smx, LLC
- Smyth The Loyalist
- Snack Naturally LLC
- Snow City Arts Foundation
- So Ill Apparel And Decals, LLC
- Social Bistro
- Social Insure Group
- Sodexo America, LLC
- Sodexomagic, LLC
- Soft Cost Consulting
- Soho House Chicago
- Soju Bbq
- Sola Salon Studio
- Sole' Resale Boutique
- Soliant Consulting, INC.
- Solidcore
- Solo Salon
- Solo Washington P.C.
- Solstice Mobile
- Something For Seniors
- Somos Salon
- Sonder
- Sonder Hotel
- Sonnets Academy - West Loop
- Soothsayer Hot Sauce, LLC
- Soul & Smoke
- Soul House
- Source Alliance Network, LLC
- Source Transport, LLC
- Source Works Development, LLC
- South Loop Cleaners
- Southern Glazer's Of Il
- Sovereign Chicago
- Sp Plus LLC
- Spa Space
- Space Opera Studio LLC
- Spaderma West Loop
- Span Studio LLC
- Spanish Acueducto
- Spantree Technology Group LLC
- Sparketing LLC
- Sparkle Nail Salon
- Sparkle Nail Salon
- Sparkle Nail Salon, LLC
- Sparrow Coffee Roastery
- Spavia West Loop
- Special Olympics Illinois
- Specialized Chicago Fulton Market
- Spectrum Sports Bar & Grill, INC.
- Speedpro Imaging Of Chicago
- Speedpro Imaging Of Chicago
- Spirit Halloween Superstores LLC
- Spiritualscents
- Splash Closet
- Spot Cleaners
- Spring Awakening LLC
- Spv Gold Valet
- Sram LLC