- Salon 54
- Salon 833
- Salon Buzz
- Salon Distefano
- Salon Duo And Spa
- Salon Lofts
- Salon Lofts
- Salon O Sixty-five
- Salon Snob
- Salon Vie Rebelle
- Salt And Light Coalition, NFP
- Saltshaker Productions
- Salveo Lifestyle
- Sam Kori George Atelier
- Sam's Cleaners & Tailor
- Samuel & Sons
- Sanctuary
- Sandburg Cleaners
- Sandra George
- Sara Jane INC
- Sarah Carstens
- Sarah Simons Reed
- Saraya And More INC.
- Sarpinos Pizzeria
- Savage Smyth, L.L.C.
- Savanna King
- Savanna King
- Saveplac Plywood Corp
- Sayat Nova
- Sayri INC.
- Sbarro LLC
- Sc Old Town LLC
- Scandia Down
- Scarlet & Company
- Scenthound Chicago Old Town
- Scepter Group
- Scheck & Siress Prosthetics, INC.
- Schedule 1 Therapeutics, INC.
- Schneider Deli
- Scholarship Event & Fashion Show
- School House Chicago
- Schuler & Shook
- Scoops Dessert Bar
- Scott Patrick
- Scruples Ii Hair Salon
- Second City Headshots
- Second City Wanderlust Photography
- Second Story Bar
- Secure Parking
- Sedgwick Studio
- See INC.
- Seed & Shell
- Segis-usa INC
- Seiler Consulting, LTD
- Select Physical Therapy
- Selena Gonzalez
- Selina Chicago / Howm
- Senior Helpers Of Chicago
- Seoul Taco
- Sephora #336
- Serafin & Assoc
- Serena's
- Serra Spring & Manufacturing LLC
- Servicemaster Restoration By Simons
- Sevgen Consulting LLC
- Sexton Cleaners
- Shadowbox LLC
- Shake Shack
- Shamila Fine Jewelry
- Shang Noodle Streeterville
- Shapiro + Raj
- Shareasale.com, INC.
- Shared Interest Boating LLC
- Sharks Fish & Chicken
- Sharon Krohn Consulting
- Shauna Johnston LLC
- Shaw Contract Group
- Shaw's Crab House
- Shay's Valet Parking INC.
- Shayda Shams
- She-nannigan's House Of Beers
- Shea Decoste Studio
- Sheaira Gill / Ld Created LLC
- Sheen Cleaners
- Sheetal Shah
- Sheffield Asset Management, L.L.C.
- Shehed Bakery LLC
- Sheraton Grand Chicago Riverwalk
- Sheraton Hotel/towers
- Sherry Koppel Design
- Sherry's Food Mart
- Sherwin Beach Press
- Shift
- Shift Clothier, INC.
- Shirley Hamilton, INC.
- Shirley Ryan Ability Lab
- Shop Smart LLC
- Shoreline Marine Company
- Shred415
- Sidney Garber
- Siemens Medical Solutions Usa, INC.
- Siena Tavern
- Sievo INC.
- Sifr
- Siga Cover INC.
- Sign Freaks
- Signal Flow LLC
- Signature Room At The 95th
- Silky Beauty Salon
- Silom 12 Express
- Silver Lady Vintage
- Silver Spoon Restaurant
- Simeone Deary Design Group
- Simon & Lilly Group
- Simonmed Imaging
- Simple Mills
- Simple Truth Communication Partners
- Simply Smart Technology
- Sirius Valet Parking INC.
- Sister's Skin Care & Waxing
- Sittercity
- Sittercity Incorporated
- Sizl
- Skims
- Skin Bar And Studio
- Skin Laser & Medspa
- Skin One
- Skinovatio Medical Spa
- Skoog Productions LLC
- Skrebneski INC
- Sky Zone Chicago Lincoln Park
- Slant Of Light Books
- Slice And Share LLC
- Sloomoo Institute
- Slow Boat Education LLC
- Slumber Stay LLC
- Small Cheval
- Smart Choice Mri, LLC
- Smart Marketing
- Smart Valet Parking
- Smartechs, LLC
- Smiledirectclub
- Smith & Larkin Interior Design
- Smith & Wollensky
- Smithbucklin Corporation
- Smoke Outlet
- Smokepost
- Smokers Planet
- Smoothie Rx
- Smoulder
- Smy Media, INC.
- Snaidero Chicago
- Snicker's Bar & Grill
- Soar
- Social Capital Partnerships
- Sofitel Chicago Magnificent Mile
- Softchoice Corporation
- Soju Chicken / Soju Burgers / Soju Express
- Sola Salon Studios
- Solidcore
- Solita
- Soma Intimates, LLC #5013
- Somerset/pandan
- Something More Goods
- Sonder Hotel
- Sonder USA INC.
- Sonesta Es Suites Chicago Downtown
- Sonesta Es Suites Chicago Downtown
- Sonnets Academy - River North
- Sonny J Mcdaniels
- Soo Chang Fineart
- Sorsby Financial Corp
- Sotheby's
- Soul Vibez
- Soul Vibez
- Soulcycle
- Sound-bar
- Source Healing INC.
- Soustech LLC
- South Side Stories Property Management
- Southern Cut Barbecue
- Souvenir City Chicago
- Sovran Beauty, LLC
- Sp Plus Corporation
- Spa Boutique Godfrey
- Spa Dabin Nail Of Old Town
- Spa Dabin Nails Of Old Town
- Spa Emilia INC
- Spa O 240
- Spa O 33
- Space519
- Spacetime Floatation Center
- Spacetime Floatation Center
- Sparrow
- Spartan Surfaces, LLC
- Spec Furniture INC.
- Specifit
- Spectrum Real Estate Properties, INC.
- Spencer Stuart
- Spencer Weisz Galleries, LTD