- Sperco Associates, INC.
- Sperco Technology Group, LLC
- Sphynx
- Spiaggia/cafe Spiaggia
- Spin Artist
- Spin Chicago
- Spins LLC
- Spirits & Spice
- Sportclips
- Sports Card Diplomat
- Sportsclips Haircuts
- Spring Brook Marine Group
- Sprinkles Cupcakes Il, LLC
- Spruce Waters Investments
- Spv Gold Valet
- Spy Bar
- Squishable.com, INC.
- Ss Threading Studio
- St Chrysostom's Church Day School
- St Clair & Grand Garage
- St Roger Abbey
- St. Clair Hotel
- St. Croix Shop
- St. Croix Shop
- Stacy Scheinberg
- Stacy Schikman
- Stacy Sweat Designs
- Stadium Games
- Stadium Goods
- Stan's Donuts Chicago, LLC
- Standing Room Only INC.
- Stans Donuts Erie Street
- Stantec Consulting Services INC
- Star Of Siam
- Star Of Siam Restaurant
- Starbuck's Coffee
- Starbucks Coffee #22423
- Starbucks Navy Pier
- Starbucks Reserve Roastery Chicago
- Stardust Lounge
- Startup Founder Daily
- Stasias Art
- State Street Barbers
- State Street Barbers
- Stc Technologies
- Steak 48
- Steelcase INC.
- Stella Mso, LLC
- Stellar Chicago
- Stellar Performance Manufacturing, LLC
- Stephanie Fritze
- Sterling Bay Property Management
- Sterling Partners
- Sterling Partners Equity Advisors LLC
- Sterling Partners Quantitative Investments LLC
- Steven Deer Salon
- Stewart Talent Management Corporation
- Stil Salon And Spa
- Stin Studio
- Stk Chicago
- Stokastic
- Stone Island Usa, INC.
- Stoneking Surface Pros
- Stoneliving Securities LLC
- Stoneside Blinds & Shades
- Stop And Shop For U
- Stop Parking
- Storagemart
- Storck USA
- Storibox Technologies, INC.
- Story & Reach
- Story & Reach Communications
- Storycatchers Theatre
- Storyville
- Str LLC
- Strata Asset Services, LLC
- Street Dreams And Avenues LLC
- Streeters Tavern
- Strength Society
- Strides By Miyanna
- String A Strand
- String It Racquet Stringing Service
- Strive Village
- Structured Markets INC.
- Stuart Rogers LTD
- Stuart-dean Co. INC.
- Studentscout
- Studio Ak
- Studio Blue, INC.
- Studio By Garden Streets
- Studio David M.
- Studio Debonair LLC
- Studio Fala Moves
- Studio Gee
- Studio Iii
- Studio J9 LLC
- Studio Kast
- Studio Lagree
- Studio One Digital, INC.
- Studio Onyx 001
- Studio Spicuzza
- Studio Xfinity
- Studs
- Stylisee Microblading LLC
- Su Casa
- Sub-zero Wolf Showroom
- Subway
- Subway
- Subway
- Subway
- Subway
- Subway
- Subway
- Subway
- Subway 24379
- Subway 42180
- Subway 50886
- Subway 5183
- Sudler Property Management
- Sugar Factory
- Sugaring Chicago LLC
- Sugaring Nyc
- Suite Home Chicago
- Suite Home Services
- Suitsupply
- Sukai Dessert Bar
- Sully's House
- Summer Azure
- Summer Classics
- Summer House Santa Monica/blues Hog Barbecue
- Sunda
- Sunny Bowls
- Sunny Bowls
- Sunny Side Up
- Sunnyside*
- Sunset Publishing Corporation
- Sunstone East Grand, LLC
- Suntory Global Spirits INC.
- Supercuts
- Superfile, INC.
- Superior Chicago Tutoring
- Superior Liquor & Wine
- Superslo Bakery
- Supplipad
- Sur La Table
- Surf's Up Old Town
- Surge Creates
- Sushi - San Hogapalooza
- Sushi Avenue, INC.
- Sushi By Bou
- Suzanne Lovell INC.
- Swanky Nails
- Swanky Nails & Spa
- Swanky Nails Salon
- Swarovski 371
- Sweat
- Sweathouz
- Sweet Mana
- Sweet Mandy B's
- Sweet Vegan Bakes
- Sweetgreen
- Sweetwaters Coffee & Tea Newcity
- Sweetwaters Coffee & Tea Newcity
- Swerve Salon
- Swift Passport And Visa Services
- Swiss Crown USA
- Swoon Living
- Sydney Paquette
- Sydplayeat LLC
- Sylvia Gehbauer
- Symmetri Marketing Group
- Symmetry Center: The Trainer's Gym
- Syska Hennessy Group, INC.
- T & E
- T & N Chicago
- T-mobile
- T. Hall Wood & Design
- T.l. Polk Industries
- Tabaq Restaurant
- Taber Studios
- Tabo Sushi By Takashi, LLC
- Taco Bell
- Taco Bell Cantina
- Taco Bell Cantina
- Taco Maya
- Tactile Craftworks LLC
- Tadas Raudzius Photography Videography
- Tag Manufacturing LLC
- Tailored Grooming
- Tails Custom Tailor
- Tails Dryclean DBA Grace Eunhye Park
- Tails In The City
- Tailwind Roasting
- Talbott Hotel
- Talc & Tonic Salon LLC.
- Talie Jane Interiors Corp
- Tamara Gruner Photography
- Tamarkin Camera
- Tandym, INC.
- Tangerine Promotions